NS35 and not vp7 is the soluble rotavirus protein which binds to target cells

Purified recombinant rotavirus VP7 forms soluble, calcium-dependent trimers.

Rotavirus is a major cause of severe, dehydrating childhood diarrhea. VP7, the rotavirus outer capsid glycoprotein, is a target of protective antibodies and is responsible for the calcium-dependent uncoating of the virus during cell entry. We have purified, characterized, and crystallized recombinant rhesus rotavirus VP7, expressed in insect cells. A critical aspect of the purification is the e...

Cloning of Rotavirus Outer Capsid Protein (VP7) Gene into the pGEM Vector

Challenging for Expression Bovine Rotavirus (RF Strain) Full-Length VP7 Protein in Prokaryotic System

Background and Aims: Rotavirus enteritis is an acute viral infectious disease among infants. VP7 protein has a key role in attachment and entry virus into the target cell. The VP7 protein is involved in inducing the production of neutralizing antibodies that protect infants against reinfection of the virus. The aim of this study was to heterologous expression of the VP7 gene of bovine rotavirus...

it is not possible to understand developments of a country’s culture and civilization without knowing his believes and myths. whether it is north or south, east or west, planes or mountains, sahara or deserts, here in iran every corner includes valuable and precious treasures which are known all over the world, and cultural – historical objects which are found here adorn all well known museums of the globe. zagros mountains, lorestan province locating at the heart of that, are not only the same, but are more prominent than other iranian regions. you can not find someone who does not know what the lorestani bronzes are, and there is no museum that not be pride of having a piece of that. the said bronzes which are manufactured four millenniums b.c. are admired nearly by all those researchers because of their beauty, diversity and technique. lorestani artistic works including stone engraves, bronzes and clays, show an ideal and metaphysical world beside real world which explain mental system of human beings on that era against sensations and phenomena happening around them. men main mental occupation on that time was he unknown world which had surrounded them, and they used to use the religion to fight life’s natural factors, and art was a tool of religious and mythical painting which was far from reality and had entered into the abstract domain. as natural objects have become subjects of lorestani art, it cleanses them from any non – intrinsic limitations and external factors which surround them and darken their meanings, and just shows their main specifications. artist in the said civilization is not searching for realism. although these are few works showing the nature, but in effect there is no wish to imitate touchable factors of the nature, and artist has turned real phenomena to encoded signs as per his own mentality. this procedure is called stylization.

it is not possible to understand developments of a country’s culture and civilization without knowing his believes and myths. whether it is north or south, east or west, planes or mountains, sahara or deserts, here in iran every corner includes valuable and precious treasures which are known all over the world, and cultural – historical objects which are found here adorn all well known museums...

Islet Amyloid Polypeptide is not a Target Antigen for CD8+ T-Cells in Type 2 Diabetes

Background: Type 2 diabetes (T2D) is a chronic metabolic disorder in which beta-cells are destroyed. The islet amyloid polypeptide (IAPP) produced by beta-cells has been reported to influence beta-cell destruction. Objective: To evaluate if IAPP can act as an autoantigen and therefore, to see if CD8 + T-cells specific for this protein might be present in T2D patients. Methods: Peripheral blood ...